{"product_id":"sos1-polyclonal-antibody-bt-ap14373","title":"SOS1 Polyclonal Antibody - BT-AP14373","description":"\u003cp\u003eSOS1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14373-20, BT-AP14373-50, BT-AP14373-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SOS1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Son of sevenless homolog 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q07889; Mouse: Q62245\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Son of sevenless homolog 1;SOS-1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6654\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239357636787,"sku":"BT-AP14373-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239357669555,"sku":"BT-AP14373-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239357702323,"sku":"BT-AP14373-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b7b91fcd-5732-406c-86ca-9773930f126f.png?v=1769393449","url":"https:\/\/afsbio.com\/products\/sos1-polyclonal-antibody-bt-ap14373","provider":"AFSBio Inc.","version":"1.0","type":"link"}