{"product_id":"sox-2-monoclonal-antibody-bt-mca1153","title":"SOX-2 Monoclonal Antibody - BT-MCA1153","description":"\u003cp\u003eSOX-2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA1153-50, BT-MCA1153-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Neuroscience; Developmental biology; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SOX2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ICC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Transcription factor SOX-2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P48431; Mouse: P48432\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SOX2; Transcription factor SOX-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6657\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238758080691,"sku":"BT-MCA1153-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238758113459,"sku":"BT-MCA1153-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ce18c0fe-dced-4a8b-bf98-75b23e5542b7.png?v=1769384440","url":"https:\/\/afsbio.com\/products\/sox-2-monoclonal-antibody-bt-mca1153","provider":"AFSBio Inc.","version":"1.0","type":"link"}