{"product_id":"sp1-polyclonal-antibody-bt-ap08473","title":"Sp1 Polyclonal Antibody - BT-AP08473","description":"\u003cp\u003eSp1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08473-20, BT-AP08473-50, BT-AP08473-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by SP1 (Sp1 transcription factor) is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for SP1.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SP1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Sp1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 80693\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P08047; Mouse: O89090; Rat: Q01714\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SP1; TSFP1; Transcription factor Sp1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6667; Mouse: 20683; Rat: 24790\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239916331187,"sku":"BT-AP08473-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239916363955,"sku":"BT-AP08473-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239916396723,"sku":"BT-AP08473-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_36f820f5-ceff-4282-9452-e71277ecf154.png?v=1769400876","url":"https:\/\/afsbio.com\/products\/sp1-polyclonal-antibody-bt-ap08473","provider":"AFSBio Inc.","version":"1.0","type":"link"}