{"product_id":"sp110-polyclonal-antibody-e-ab-66193","title":"SP110 Polyclonal Antibody - E-AB-66193","description":"\u003cp\u003eSP110 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-66193-60, E-AB-66193-120, E-AB-66193-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: SP110\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: SP110; IFI41; IFI75; IPR1; VODI\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9HB58\u003c\/p\u003e\n\n\u003cp\u003eBackground: The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100\/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human SP110\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 28kDa\/46kDa\/61kDa\/62kDa\/78kDa\/81kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 80kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146409443507,"sku":"E-AB-66193-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146409476275,"sku":"E-AB-66193-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146409509043,"sku":"E-AB-66193-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_4bb171c9-dfd9-4d97-93b5-cf06b0dae7cc.png?v=1710295062","url":"https:\/\/afsbio.com\/products\/sp110-polyclonal-antibody-e-ab-66193","provider":"AFSBio Inc.","version":"1.0","type":"link"}