{"product_id":"spak-polyclonal-antibody-bt-ap08492","title":"SPAK Polyclonal Antibody - BT-AP08492","description":"\u003cp\u003eSPAK Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08492-20, BT-AP08492-50, BT-AP08492-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: STK39 encodes a serine\/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: STK39\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SPAK Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 59642\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9UEW8; Mouse: Q9Z1W9; Rat: O88506\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: STK39; SPAK; STE20\/SPS1-related proline-alanine-rich protein kinase; Ste-20-related kinase; DCHT; Serine\/threonine-protein kinase 39\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 27347; Mouse: 53416; Rat: 54348\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239917117619,"sku":"BT-AP08492-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239917150387,"sku":"BT-AP08492-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239917183155,"sku":"BT-AP08492-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_649996da-71e3-41a3-b01d-738169a1976f.png?v=1769400888","url":"https:\/\/afsbio.com\/products\/spak-polyclonal-antibody-bt-ap08492","provider":"AFSBio Inc.","version":"1.0","type":"link"}