{"product_id":"sparc-rabbit-pab-es4251","title":"SPARC rabbit pAb - ES4251","description":"\u003cp\u003eSPARC rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES4251-50, ES4251-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2015],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: SPARC; ON; SPARC; Basement-membrane protein 40; BM-40; Osteonectin; ON; Secreted protein acidic and rich in cysteine\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. IHC-p: 1:100-1:300. ELISA: 1\/20000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human SPARC. AA range:141-190\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 34kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 6678\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P09486\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Secreted, extracellular space, extracellular matrix, basement membrane. In or around the basement membrane.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202186338483,"sku":"ES4251-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202186371251,"sku":"ES4251-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_3d71bfb3-0387-47d8-89f2-27f5350e2edb.png?v=1767123806","url":"https:\/\/afsbio.com\/products\/sparc-rabbit-pab-es4251","provider":"AFSBio Inc.","version":"1.0","type":"link"}