{"product_id":"spast-polyclonal-antibody-e-ab-16442","title":"SPAST Polyclonal Antibody - E-AB-16442","description":"\u003cp\u003eSPAST Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-16442-60, E-AB-16442-120, E-AB-16442-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: SPAST\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ADPSP; FSP 2; FSP2; KIAA1083; Spast; spastic paraplegia 4 (autosomal dominant; spastin); Spastic paraplegia 4; spastin; SPG 4; SPG4; SPG4 gene\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9UBP0\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.6 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human SPAST\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43130627424435,"sku":"E-AB-16442-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43130627457203,"sku":"E-AB-16442-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43130627489971,"sku":"E-AB-16442-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_6a4a7ecd-67a9-4b1a-8f11-89f978769b50.png?v=1709810352","url":"https:\/\/afsbio.com\/products\/spast-polyclonal-antibody-e-ab-16442","provider":"AFSBio Inc.","version":"1.0","type":"link"}