{"product_id":"spg16-rabbit-polyclonal-antibody-es12992","title":"SPG16 Rabbit Polyclonal Antibody - ES12992","description":"\u003cp\u003eSPG16 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES12992-50, ES12992-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cilia and flagella are comprised of a microtubular backbone, the axoneme, which is organized by the basal body and surrounded by plasma membrane. SPAG16 encodes 2 major proteins that associate with the axoneme of sperm tail and the nucleus of postmeiotic germ cells, respectively (Zhang et al., 2007 [PubMed 17699735]).[supplied by OMIM, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA, IHC\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human SPG16 AA range: 520-570\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: SPG16\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of SPG16 at Human\/Mouse\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000, IHC-p 1:50-300, ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Isoform 1 is detected in testis, Isoform 4 is detected in testis and brain, and at lower levels in kidney, heart, pancreas, thyroid, ovary, adrenal gland, spinal cord, trachea and liver,\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 69kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Function: Necessary for sperm flagellar function\u003cbr\u003e\nSimilarity: Contains 7 WD repeats\u003cbr\u003e\nSubcellular Location: Detected on the sperm flagellum. Detected in the central apparatus of the axoneme. Colocalizes with SPAG6 on microtubules\u003cbr\u003e\nSubunit: Interacts with SPAG6\u003cbr\u003e\nTissue Specificity: Isoform 1 is detected in testis. Isoform 4 is detected in testis and brain, and at lower levels in kidney, heart, pancreas, thyroid, ovary, adrenal gland, spinal cord, trachea and liver\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Cytoplasm Cytoplasm, cytoskeleton, flagellum axoneme Cytoplasm, cytoskeleton, cilium axoneme Cell projection, cilium, flagellum Detected on the sperm flagellum axoneme Detected in the central apparatus of the axoneme Colocalizes with SPAG6 on microtubules (By similarity)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: SPAG16 PF20\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: SPG16\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 66722\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q8K450\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46315003805875,"sku":"ES12992-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46315003838643,"sku":"ES12992-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/spg16-rabbit-polyclonal-antibody-es12992","provider":"AFSBio Inc.","version":"1.0","type":"link"}