{"product_id":"spg7-polyclonal-antibody-bt-ap14419","title":"SPG7 Polyclonal Antibody - BT-AP14419","description":"\u003cp\u003eSPG7 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14419-20, BT-AP14419-50, BT-AP14419-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SPG7\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Paraplegin\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9UQ90; Mouse: Q3ULF4; Rat: Q7TT47\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Paraplegin;EC 3.4.24.-;Spastic paraplegia 7 protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6687\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239361372339,"sku":"BT-AP14419-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239361405107,"sku":"BT-AP14419-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239361437875,"sku":"BT-AP14419-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f6d03028-59a0-4ed9-9b16-1e48fd6b6fc5.png?v=1769393492","url":"https:\/\/afsbio.com\/products\/spg7-polyclonal-antibody-bt-ap14419","provider":"AFSBio Inc.","version":"1.0","type":"link"}