{"product_id":"sphk1-phospho-ser225-rabbit-polyclonal-antibody-ra36797","title":"SPHK1 (Phospho-Ser225) Rabbit Polyclonal Antibody - RA36797","description":"\u003cp\u003eSPHK1 (Phospho-Ser225) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA36797-50, RA36797-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: sphingosine kinase 1 (SPHK1) Homo sapiens The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],\u003c\/p\u003e \n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Sphingosine kinase 1 (SK 1) (SPK 1) (EC 2.7.1.91)\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 42\u003c\/p\u003e\n\n\u003cp\u003eProtein Molecular Weight (kDa): 42\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 8877\u003c\/p\u003e\n\n\u003cp\u003eHuman SwissProt Number: Q9NYA1\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, and 0.110% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50μL","offer_id":45122495119539,"sku":"RA36797-50","price":360.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122495152307,"sku":"RA36797-100","price":480.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Reed_Product_image1.png?v=1787773798","url":"https:\/\/afsbio.com\/products\/sphk1-phospho-ser225-rabbit-polyclonal-antibody-ra36797","provider":"AFSBio Inc.","version":"1.0","type":"link"}