{"product_id":"spindlin-1-h139-polyclonal-antibody-bs2678","title":"Spindlin-1 (H139) Polyclonal Antibody-BS2678","description":"\u003cp\u003eSpindlin-1 (H139) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS2678-50, BS2678-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9Y657\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eBackground: SPIN1 (spindlin 1), also known as SPIN or ovarian cancer-related protein (OCR), is a 262 amino acid nuclear protein suggested to play a role in regulation of the cell-cycle during the transition from gamete to embryo. A member of the SPIN\/STSY family, SPIN1 localizes to interphase nucleus and mitotic chromosomes, and is modified by phosphorylation in a cell-cycle-dependent fashion. A meiotic spindle-binding protein, SPIN1 overexpression has been shown to cause defects in mitotic spindles, thereby resulting in chromosome instability and potential tumorigenesis.\u003c\/p\u003e \n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Spindlin-1 (H139) polyclonal antibody detects endogenous levels of Spindlin-1 protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Spindlin-1 (H139) pAb at 1:500 dilution\u003cbr\u003e\nLane 1: SK-OVCAR3 whole cell lysate (40ug)\u003cbr\u003e\nLane 2: SGC7901 whole cell lysate (40ug)\u003cbr\u003e\nLane 3: The Ovarian tissue lysate of Rat (40ug)\u003cbr\u003e\nLane 4: The Testis tissue lysate of Mouse (40ug), Immunohistochemistry (IHC) analyzes of Spindlin-1 (H139) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.\u003c\/p\u003e \n\n\u003cp\u003eBioworld Molecular Weight: ~ 30 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: OCR; Ovarian cancer-related protein; SPIN; Spin1; SPIN1; Spindlin 1;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 110-156 of Human Spindlin-1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42953228779699,"sku":"BS2678-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42953228812467,"sku":"BS2678-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_67ad4ee1-6288-443d-8fb3-526caf804f92.jpg?v=1705057228","url":"https:\/\/afsbio.com\/products\/spindlin-1-h139-polyclonal-antibody-bs2678","provider":"AFSBio Inc.","version":"1.0","type":"link"}