{"product_id":"splicing-factor-1-polyclonal-antibody-ra29999","title":"Splicing factor 1 Polyclonal Antibody - RA29999","description":"Splicing factor 1 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA29999-50, RA29999-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: splicing factor 1 (SF1) Homo sapiens This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. Immunofluorescence: 1\/200 - 1\/1000. ELISA: 1\/20000. Not yet tested in other applications.\n\nAlternative Names: SF1; ZFM1; ZNF162; Splicing factor 1; Mammalian branch point-binding protein; BBP; mBBP; Transcription factor ZFM1; Zinc finger gene in MEN1 locus; Zinc finger protein 162\n\nApplications: WB; IHC-p; IF\/ICC; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse\n\nGeneID (Human): 7536\n\nProtein MW (KDa): 68\n\nSWISS: Q15637\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122418311347,"sku":"RA29999-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122418344115,"sku":"RA29999-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_78ee4461-0d20-4677-b20c-b7eaf28432e9.png?v=1773348661","url":"https:\/\/afsbio.com\/products\/splicing-factor-1-polyclonal-antibody-ra29999","provider":"AFSBio Inc.","version":"1.0","type":"link"}