{"product_id":"spre1-polyclonal-antibody-bt-ap14433","title":"SPRE1 Polyclonal Antibody - BT-AP14433","description":"\u003cp\u003eSPRE1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14433-20, BT-AP14433-50, BT-AP14433-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SPRED1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Sprouty-related, EVH1 domain-containing protein 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q7Z699; Mouse: Q924S8\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Sprouty-related, EVH1 domain-containing protein 1;Spred-1;hSpred1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 161742\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239362289843,"sku":"BT-AP14433-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239362322611,"sku":"BT-AP14433-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239362355379,"sku":"BT-AP14433-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_97c59e8a-65ba-4cf4-84f4-50d5351c04d6.png?v=1769393508","url":"https:\/\/afsbio.com\/products\/spre1-polyclonal-antibody-bt-ap14433","provider":"AFSBio Inc.","version":"1.0","type":"link"}