{"product_id":"sptlc1-polyclonal-antibody-ra30009","title":"SPTLC1 Polyclonal Antibody - RA30009","description":"SPTLC1 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA30009-50, RA30009-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: serine palmitoyltransferase long chain base subunit 1 (SPTLC1) Homo sapiens This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. [provided by RefSeq, Jul 2013],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. IHC-p: 1:100-300 ELISA: 1\/20000. Not yet tested in other applications.\n\nAlternative Names: SPTLC1; LCB1; Serine palmitoyltransferase 1; Long chain base biosynthesis protein 1; LCB 1; Serine-palmitoyl-CoA transferase 1; SPT 1; SPT1\n\nApplications: WB; IHC-p; IF (paraffin section) ; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 10558\n\nProtein MW (KDa): 52\n\nSWISS: O15269\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122418573491,"sku":"RA30009-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122418606259,"sku":"RA30009-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d378f7fd-c604-4a89-a39a-7231f2eb162a.png?v=1773348664","url":"https:\/\/afsbio.com\/products\/sptlc1-polyclonal-antibody-ra30009","provider":"AFSBio Inc.","version":"1.0","type":"link"}