{"product_id":"sqstm1-monoclonal-antibody-bt-mca4761","title":"SQSTM1 Monoclonal Antibody - BT-MCA4761","description":"\u003cp\u003eSQSTM1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4761-50, BT-MCA4761-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding\/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling, Cancer, Signal transduction, Cardiovascular, Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SQSTM1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 5H7E2\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SQSTM1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 47.7kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q13501\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: p60, p62, A170, OSIL, PDB3, ZIP3, p62B\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 8878\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238567764147,"sku":"BT-MCA4761-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238567796915,"sku":"BT-MCA4761-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d3588712-ae06-45bc-b563-2a52721fdc60.png?v=1769382657","url":"https:\/\/afsbio.com\/products\/sqstm1-monoclonal-antibody-bt-mca4761","provider":"AFSBio Inc.","version":"1.0","type":"link"}