{"product_id":"sqstm1-p62-phospho-thr269-ser272-rabbit-polyclonal-antibody-bt-ap04880","title":"SQSTM1\/p62 (Phospho-Thr269\/Ser272) Rabbit Polyclonal Antibody - BT-AP04880","description":"\u003cp\u003eSQSTM1\/p62 (Phospho-Thr269\/Ser272) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04880-20, BT-AP04880-50, BT-AP04880-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding\/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Cancer; Signal transduction; Cardiovascular; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SQSTM1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SQSTM1\/p62\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q13501; Mouse: Q64337; Rat: O08623\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SQSTM1\/p62;Thr269\/Ser272; Sequestosome-1; EBI3-associated protein of 60 kDa; EBIAP; p60; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; Ubiquitin-binding protein p62\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8878; Mouse: 18412; Rat: 113894\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239024255155,"sku":"BT-AP04880-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239024287923,"sku":"BT-AP04880-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239024320691,"sku":"BT-AP04880-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_850d1edd-a0fe-4175-848e-e11e53f4db6a.png?v=1769388061","url":"https:\/\/afsbio.com\/products\/sqstm1-p62-phospho-thr269-ser272-rabbit-polyclonal-antibody-bt-ap04880","provider":"AFSBio Inc.","version":"1.0","type":"link"}