{"product_id":"src-phospho-ser17-rabbit-polyclonal-antibody-bt-ap04885","title":"Src (Phospho-Ser17) Rabbit Polyclonal Antibody - BT-AP04885","description":"\u003cp\u003eSrc (Phospho-Ser17) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04885-20, BT-AP04885-50, BT-AP04885-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Cancer; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SRC\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Src\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P12931; Mouse: P05480; Rat: Q9WUD9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Src;Ser17; Proto-oncogene tyrosine-protein kinase Src; EC 2.7.10.2; Proto-oncogene c-Src; pp60c-src; p60-Src\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6714; Mouse: 20779\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239024353459,"sku":"BT-AP04885-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239024386227,"sku":"BT-AP04885-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239024418995,"sku":"BT-AP04885-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f356b138-69a4-4d70-8dd0-a80bdc558edc.png?v=1769388062","url":"https:\/\/afsbio.com\/products\/src-phospho-ser17-rabbit-polyclonal-antibody-bt-ap04885","provider":"AFSBio Inc.","version":"1.0","type":"link"}