{"product_id":"srf-phospho-s103-polyclonal-antibody-bs4177","title":"SRF (phospho-S103) Polyclonal Antibody-BS4177","description":"\u003cp\u003eSRF (phospho-S103) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS4177-50, BS4177-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P11831\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSRF (phospho-S103) Polyclonal Antibody-BS4177\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003cbr\u003e\nIHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promotor elements in many muscle-specific promotors. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1) have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino-terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: p-SRF (S103) polyclonal antibody detects endogenous levels of SRF protein when phosphorylated at Ser103.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 52 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of SRF (phospho-S103) polyclonal antibody at 1:500 dilution\u003cbr\u003e\n Lane 1: H1792 whole cell lysate (40ug) \u003cbr\u003e\n Lane 2: SK-OVCAR3 whole cell lysate (40ug) \u003cbr\u003e\n Lane 3: HEK293T whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of p-SRF (S103) pAb in paraffin-embedded human lung cancer tissue.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Serum response factor\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic phosphopeptide derived from human SRF around the phosphorylation site of Serine 103.\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylation\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42957296631987,"sku":"BS4177-50","price":276.71,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42957296664755,"sku":"BS4177-100","price":490.83,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_98f54caf-cb93-4730-aa64-b9080ba442b9.jpg?v=1705144505","url":"https:\/\/afsbio.com\/products\/srf-phospho-s103-polyclonal-antibody-bs4177","provider":"AFSBio Inc.","version":"1.0","type":"link"}