{"product_id":"ssbp2-polyclonal-antibody-bs5946","title":"SSBP2 Polyclonal Antibody-BS5946","description":"\u003cp\u003eSSBP2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS5946-50, BS5946-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P81877\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003cbr\u003e\nIHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells, as well as in mitochondria, bacteria and viruses. SSBP2 (single-stranded DNA binding protein 2), also known as SSDP2, is a 361 amino acid protein that localizes to the nucleus and contains one LisH domain. Expressed ubiquitously, SSBP2 is thought to induce growth arrest in cancer cells and may, therefore, function as a potent tumor suppressor. The gene encoding SSBP2 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Defects in chromosome 5-associated genes are related to the pathogenesis of Cockayne syndrome, familial adenomatous polyposis and Treacher Collins syndrome.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: SSBP2 polyclonal antibody detects endogenous levels of SSBP2 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 38 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of SSBP2 polyclonal antibody at 1:500 dilution\u003cbr\u003e\n Lane 1: HEK293T cell lysate\u003cbr\u003e\n Lane 2: NIH-3T3 cell lysate\u003cbr\u003e\n Lane 3: Rat kidney tissue lysate, Immunohistochemistry (IHC) analyzes of SSBP2 pAb in paraffin-embedded human colon carcinoma tissue at 1:5000. cytoplasmic and nucleus staining. Negative control (the right) Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase., Immunohistochemistry (IHC) analyzes of SSBP2 pAb in paraffin-embedded human kidney carcinoma tissue at 1:5000. cytoplasmic and nucleus staining. Negative control (the right) Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Single-stranded DNA-binding protein 2; Sequence-specific single-stranded-DNA-binding protein 2; SSBP2; SSDP2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 2-47 of Human SSBP2.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42993801953459,"sku":"BS5946-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42993801986227,"sku":"BS5946-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_3ea71b19-3ee2-4d12-a0d5-ade9208673ce.jpg?v=1706183709","url":"https:\/\/afsbio.com\/products\/ssbp2-polyclonal-antibody-bs5946","provider":"AFSBio Inc.","version":"1.0","type":"link"}