{"product_id":"ssh3-rabbit-pab-es3503","title":"SSH3 rabbit pAb - ES3503","description":"\u003cp\u003eSSH3 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES3503-50, ES3503-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The ADF (actin-depolymerizing factor)\/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF\/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF\/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM, Mar 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: SSH3; SSH3L; Protein phosphatase Slingshot homolog 3; SSH-like protein 3; SSH-3L; hSSH-3L\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/40000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human SSH3. AA range:357-406\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 74kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 54961\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q8TE77\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm, cytoskeleton. Nucleus.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202138759347,"sku":"ES3503-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202138792115,"sku":"ES3503-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_a2ccfd57-c6eb-45b5-8692-3a54d134626a.png?v=1767122810","url":"https:\/\/afsbio.com\/products\/ssh3-rabbit-pab-es3503","provider":"AFSBio Inc.","version":"1.0","type":"link"}