{"product_id":"sssca1-mouse-monoclonal-antibody-mb4047","title":"SSSCA1 Mouse Monoclonal Antibody - MB4047","description":"\u003cp\u003eSSSCA1 Mouse Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 25μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB4047-25, MB4047-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: SSSCA1 (sjogren syndrome\/scleroderma autoantigen 1), also known as p27, is a 199 amino acid protein that may play a role in mitosis. Considered a centromere-associated protein, SSSCA1 may induce anti-centromere antibodies. SSSCA1 is phosphorylated upon DNA damage by ATM or ATR. The gene encoding SSSCA1 maps to human chromosome 11, which houses over 1, 400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.\u003c\/p\u003e \n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: FC, IF, IHC, WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Protein ZNRD2, Autoantigen p27, Sjoegren syndrome\/scleroderma autoantigen 1, Zinc ribbon domain-containing protein 2, ZNRD2, SSSCA1\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fμll length human recombinant protein of human SSSCA1 (NP_006387) produced in HEK293T cell.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:2000, IF 1:100, FLOW 1:100, IHC: 1:150\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG1\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 27 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: O60232\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"25μl","offer_id":45945966493875,"sku":"MB4047-25","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45945966526643,"sku":"MB4047-100","price":642.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/sssca1-mouse-monoclonal-antibody-mb4047","provider":"AFSBio Inc.","version":"1.0","type":"link"}