{"product_id":"stag3-rabbit-pab-es4546","title":"STAG3 rabbit pAb - ES4546","description":"\u003cp\u003eSTAG3 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES4546-50, ES4546-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is expressed in the nucleus and is a subunit of the cohesin complex which regulates the cohesion of sister chromatids during cell division. A mutation in this gene is associated with premature ovarian failure. Alternate splicing results in multiple transcript variants encoding distinct isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Apr 2014],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: STAG3; Cohesin subunit SA-3; SCC3 homolog 3; Stromal antigen 3; Stromalin-3\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human STAG3. AA range:1161-1210\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 139kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 10734\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9UJ98\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus. Chromosome. Chromosome, centromere. Associates with chromatin. In prophase I stage of meiosis, it is found along the axial elements of synaptonemal complexes. In late-pachytene-diplotene, the bulk of protein dissociates from the chromosome arms probably because of phosphorylation by PLK1, except at centromeres, where cohesin complexes remain. It however remains chromatin associated at the centromeres up to metaphase I. During anaphase I, it probably dissociates from centromeres, allowing chromosomes segregation.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202201739443,"sku":"ES4546-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202201772211,"sku":"ES4546-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_d6af0177-0283-4672-bb2d-7c5cc661c89a.png?v=1767124129","url":"https:\/\/afsbio.com\/products\/stag3-rabbit-pab-es4546","provider":"AFSBio Inc.","version":"1.0","type":"link"}