{"product_id":"stc2-polyclonal-antibody-bt-ap14561","title":"STC2 Polyclonal Antibody - BT-AP14561","description":"\u003cp\u003eSTC2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14561-20, BT-AP14561-50, BT-AP14561-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium\/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: STC2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Stanniocalcin-2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O76061; Mouse: O88452; Rat: Q9R0K8\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Stanniocalcin-2;STC-2;Stanniocalcin-related protein;STC-related protein;STCRP\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8614\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239374151859,"sku":"BT-AP14561-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239374184627,"sku":"BT-AP14561-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239374217395,"sku":"BT-AP14561-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_46023b67-d954-4a41-8944-7b1b22bf7947.png?v=1769393600","url":"https:\/\/afsbio.com\/products\/stc2-polyclonal-antibody-bt-ap14561","provider":"AFSBio Inc.","version":"1.0","type":"link"}