{"product_id":"stip1-hop-rabbit-pab-es20870","title":"STIP1\/HOP Rabbit pAb - ES20870","description":"\u003cp\u003eSTIP1\/HOP Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES20870-50, ES20870-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Stress-induced-phosphoprotein 1 (STI1) (Hsc70\/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC; WB\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC-p 1:50-200, WB 1:1000-2000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human STIP1\/HOP AA range: 250-300\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 64kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 10963\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P31948\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm. Nucleus. Dynein axonemal particle.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202438455475,"sku":"ES20870-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202438488243,"sku":"ES20870-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_1e2751b6-ece3-4f24-b3bf-d7c3deb01158.png?v=1767129177","url":"https:\/\/afsbio.com\/products\/stip1-hop-rabbit-pab-es20870","provider":"AFSBio Inc.","version":"1.0","type":"link"}