{"product_id":"sucla2-polyclonal-antibody-bs70936","title":"SUCLA2 Polyclonal Antibody-BS70936","description":"\u003cp\u003eSUCLA2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS70936-50, BS70936-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9P2R7\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB 1:500 - 1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: SUCLA2 (succinate-CoA ligase, ADP-forming, beta subunit), also known as A-BETA, SCS-betaA or renal carcinoma antigen NY-REN-39, is a 463 amino acid mitochondrial matrix enzyme that belongs to the succinate\/malate CoA ligase beta subunit family. Widely expressed, SUCLA2 dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. Defects in SUCLA2 may be involved in a group of autosomal recessive disorders known as Mitochondrial DNA depletion syndromes (MDSs) that are characterized by a decrease in mitochondrial DNA copy numbers in affected tissues.\u003c\/p\u003e \n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: SUCLA2 polyclonal antibody detects endogenous levels of SUCLA2 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 50 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western Blot analysis of extracts of various cells, using SUCLA2 antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Renal carcinoma antigen NY-REN-39; SCS-betaA; SCS-βA; SCSβA;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombinant protein of human SUCLA2.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42923492769971,"sku":"BS70936-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42923492802739,"sku":"BS70936-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_ae9ff0b8-9da3-45b5-8eb0-a5834b88ca7f.jpg?v=1703850443","url":"https:\/\/afsbio.com\/products\/sucla2-polyclonal-antibody-bs70936","provider":"AFSBio Inc.","version":"1.0","type":"link"}