{"product_id":"sumo4-polyclonal-antibody-bt-ap14590","title":"SUMO4 Polyclonal Antibody - BT-AP14590","description":"\u003cp\u003eSUMO4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14590-20, BT-AP14590-50, BT-AP14590-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteinsandapos; subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Tags and cell markers; Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SUMO4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Small ubiquitin-related modifier 4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q6EEV6\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Small ubiquitin-related modifier 4;SUMO-4;Small ubiquitin-like protein 4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 387082\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239375462579,"sku":"BT-AP14590-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239375495347,"sku":"BT-AP14590-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239375528115,"sku":"BT-AP14590-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c012859c-e534-45f6-ac35-7541259584db.png?v=1769393623","url":"https:\/\/afsbio.com\/products\/sumo4-polyclonal-antibody-bt-ap14590","provider":"AFSBio Inc.","version":"1.0","type":"link"}