{"product_id":"sun1-polyclonal-antibody-bs9956m","title":"SUN1 Polyclonal Antibody-BS9956M","description":"\u003cp\u003eSUN1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS9956M-50, BS9956M-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O94901\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC ICC FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500-1:2000   IHC: 1:50-1:200\u003cbr\u003e\nICC: 1:50-1:200        FC: 1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eBackground: UNC84A (UNC84 homolog A), also known as SUN1, is a multi-pass nuclear membrane protein that is involved in nuclear anchoring and migration. Highly expressed in heart, brain and testis, UNC84A functions as an A-type Lamin-binding protein that forms a link between the inner and outer nuclear envelope membranes. This link acts as a structural bridge between the nuclear interior and the Actin cytoskeleton and is essential for proper localization of nuclear envelope proteins. Additionally, UNC84A may be involved in telomere attachment and in normal testis development. UNC84A contains one UNC84 (SUN) domain and exists as four isoforms due to alternative splicing events.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Protein A affinity purified.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of SUN1 and does not cross-react with related proteins.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 90 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of SUN1 on rat kidney tissue lysate using anti-SUN1 antibody at 1:2000 dilution., Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-SUN1 antibody. Counter stained with hematoxylin., Flow cytometric analysis of SH-SY-5Y cells with SUN1 antibody at 1\/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: SUN domain-containing protein 1; Protein unc-84 homolog A; Sad1\/unc-84 protein-like 1; SUN1; KIAA0810; UNC84A\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein corresponding to C-terminal human SUN1.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42987089985715,"sku":"BS9956M-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42987090018483,"sku":"BS9956M-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_27c79c91-2d56-49fd-b74d-0f8cdd2dd268.jpg?v=1706008914","url":"https:\/\/afsbio.com\/products\/sun1-polyclonal-antibody-bs9956m","provider":"AFSBio Inc.","version":"1.0","type":"link"}