{"product_id":"superoxide-dismutase-1-monoclonal-antibody-mb12262","title":"Superoxide Dismutase 1 Monoclonal Antibody-MB12262","description":"\u003cp\u003eSuperoxide Dismutase 1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB12262-50, MB12262-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P00441\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-F, IHC-P, ICC\/IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  IF: 1\/50-1\/200\u003c\/p\u003e  \n\n\u003cp\u003eBackground: SOD1, Cu\/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear. Mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight species that aggregate and end up in proteinaceous inclusions.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 16 kDa; Observed MW: 16 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunocytochemistry analysis of Superoxide Dismutase 1 in HCT116 using Superoxide Dismutase 1 antibody, and DAPI., Western blot analysis of Superoxide Dismutase 1 in A549, HL-60, C6 lysates using Superoxide Dismutase 1 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using Superoxide Dismutase 1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human Superoxide Dismutase 1\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43004755345587,"sku":"MB12262-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43004755378355,"sku":"MB12262-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5e374584-cd82-4865-9c43-33c9ec7e876e.jpg?v=1706445729","url":"https:\/\/afsbio.com\/products\/superoxide-dismutase-1-monoclonal-antibody-mb12262","provider":"AFSBio Inc.","version":"1.0","type":"link"}