{"product_id":"sv40-t-antigen-monoclonal-antibody-mb12265","title":"SV40 T Antigen Monoclonal Antibody-MB12265","description":"\u003cp\u003eSV40 T Antigen Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB12265-50, MB12265-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P03070\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: All\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\/IF, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IF: 1\/50-1\/200  IP: 1\/20\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA. Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 82 kDa; Observed MW: 90 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of SV40 Tantigen in A549, HL-60, U251 lysates using SV40 T Antigen antibody., Immunocytochemistry analysis of SV40 Tantigen in hela using SV40 Tantigen antibody, and DAPI\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Large T antigen; LT; LT-AG\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of SV40 T-antigen\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42975416516787,"sku":"MB12265-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42975416549555,"sku":"MB12265-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_4ae9c583-c614-42c8-bf8c-e1d5632f99c4.jpg?v=1705665686","url":"https:\/\/afsbio.com\/products\/sv40-t-antigen-monoclonal-antibody-mb12265","provider":"AFSBio Inc.","version":"1.0","type":"link"}