{"product_id":"syac-rabbit-polyclonal-antibody-bt-ap04972","title":"SYAC Rabbit Polyclonal Antibody - BT-AP04972","description":"\u003cp\u003eSYAC Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP04972-20, BT-AP04972-50, BT-AP04972-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases| of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA| and a second domain which interacts with the rest of the tRNA structure.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: AARS\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: SYAC\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P49588; Mouse: Q8BGQ7; Rat: P50475\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SYAC; Alanine--tRNA ligase; cytoplasmic; EC 6.1.1.7; Alanyl-tRNA synthetase; AlaRS; Renal carcinoma antigen NY-REN-42\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 16; Mouse: 234734; Rat: 292023\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239025795251,"sku":"BT-AP04972-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239025828019,"sku":"BT-AP04972-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239025860787,"sku":"BT-AP04972-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5604afa3-077f-495a-8ba3-d9d389ce6610.png?v=1769388081","url":"https:\/\/afsbio.com\/products\/syac-rabbit-polyclonal-antibody-bt-ap04972","provider":"AFSBio Inc.","version":"1.0","type":"link"}