{"product_id":"syne3-polyclonal-antibody-bs62409","title":"SYNE3 Polyclonal Antibody-BS62409","description":"\u003cp\u003eSYNE3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS62409-50, BS62409-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q6ZMZ3\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB  IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500~1:1000  IF:1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The protein was purified from E.coli and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: SYNE3 polyclonal antibody detects endogenous levels of SYNE3 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of SYNE3 polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLaneA:Aml-12 whole cell lysate\u003cbr\u003e\nLaneB:H9C2 whole cell lysate\u003cbr\u003e\nLaneC:A549 whole cell lysate\u003cbr\u003e\nLaneD:HepG2 whole cell lysate\u003cbr\u003e\nLaneE:HEK293T whole cell lysate\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 112 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: C14orf139; C14orf49; KASH3; LINC00341; NCRNA00341; NET53; Nesp3; Nesprin3; Nesprin 3; Nesprin-3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human SYNE3.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910456873139,"sku":"BS62409-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910456905907,"sku":"BS62409-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_53aa2e78-5bbb-4e28-b6a3-3c5616da6bb5.jpg?v=1703092772","url":"https:\/\/afsbio.com\/products\/syne3-polyclonal-antibody-bs62409","provider":"AFSBio Inc.","version":"1.0","type":"link"}