{"product_id":"synuclein-α-phospho-tyr133-polyclonal-antibody-ra30219","title":"Synuclein-α (phospho Tyr133) Polyclonal Antibody - RA30219","description":"Synuclein-α (phospho Tyr133) Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA30219-50, RA30219-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: synuclein alpha (SNCA) Homo sapiens Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/40000. Not yet tested in other applications.\n\nAlternative Names: SNCA; NACP; PARK1; Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP\n\nApplications: WB; IHC-p; IF (paraffin section) ; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 6622\n\nProtein MW (KDa): 18\n\nSWISS: P37840\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45122429485235,"sku":"RA30219-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45122429518003,"sku":"RA30219-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1465c39e-a6a9-4156-b27b-608be9b7b8df.png?v=1773348783","url":"https:\/\/afsbio.com\/products\/synuclein-%ce%b1-phospho-tyr133-polyclonal-antibody-ra30219","provider":"AFSBio Inc.","version":"1.0","type":"link"}