{"product_id":"syt14-rabbit-polyclonal-antibody-es10332","title":"SYT14 Rabbit Polyclonal Antibody - ES10332","description":"\u003cp\u003eSYT14 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES10332-50, ES10332-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: approximately 7-10 business days, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: synaptotagmin 14(SYT14) Homo sapiens This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate membrane trafficking in synaptic transmission. The encoded protein is a calcium-independent synaptotagmin. Mutations in this gene are a cause of autosomal recessive spinocerebellar ataxia-11 (SCAR11), and a t(1;3) translocation of this gene has been associated with neurodevelopmental abnormalities. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Dec 2011],\u003c\/p\u003e \n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from part region of human protein\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: SYT14,\u003c\/p\u003e \n\n\u003cp\u003eSpecificity: SYT14 Polyclonal Antibody detects endogenous levels of protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e \n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Highly expressed in fetal and adult brain tissue.\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 61kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent. Similarity: Belongs to the synaptotagmin family. Similarity: Contains 2 C2 domains. Subunit: Homodimer. Can also form heterodimers.\u003c\/p\u003e \n\n\u003cp\u003eSubcellular Location: Membrane, Single-pass type III membrane protein Localized in perinuclear and submembranous regions.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: SYT14\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Synaptotagmin-14, Synaptotagmin XIV, SytXIV\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 255928\u003c\/p\u003e\n\n\u003cp\u003eHuman SwissProt Number: Q8NB59\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q7TN84\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":45825496481971,"sku":"ES10332-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45825496514739,"sku":"ES10332-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk-biotechnology-logo-product.jpg?v=1786476023","url":"https:\/\/afsbio.com\/products\/syt14-rabbit-polyclonal-antibody-es10332","provider":"AFSBio Inc.","version":"1.0","type":"link"}