{"product_id":"syt4-rabbit-polyclonal-antibody-es10335","title":"SYT4 Rabbit Polyclonal Antibody - ES10335","description":"\u003cp\u003eSYT4 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES10335-50, ES10335-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse,\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from part region of human protein\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: SYT4\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: SYT4 Polyclonal Antibody detects endogenous levels of protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Expressed in melanocytes (PubMed:23999003), Expressed in brain, Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus (PubMed:23999003),\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 46kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Cofactor: Binds 3 calcium ions per subunit. The ions are bound to the C2 domains\u003cbr\u003e\nFunction: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis\u003cbr\u003e\nSimilarity: Belongs to the synaptotagmin family\u003cbr\u003e\nSimilarity: Contains 2 C2 domains\u003cbr\u003e\nTissue Specificity: Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle membrane, Single-pass membrane protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: SYT4 KIAA1342\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Synaptotagmin-4 (Synaptotagmin IV) (SytIV)\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: P40749\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: P50232\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46314281140403,"sku":"ES10335-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46314281173171,"sku":"ES10335-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/syt4-rabbit-polyclonal-antibody-es10335","provider":"AFSBio Inc.","version":"1.0","type":"link"}