{"product_id":"syt8-polyclonal-antibody-bt-ap14661","title":"SYT8 Polyclonal Antibody - BT-AP14661","description":"\u003cp\u003eSYT8 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14661-20, BT-AP14661-50, BT-AP14661-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the synaptotagmin protein family. Synaptotagmins are membrane proteins that are important in neurotransmission and hormone secretion, both of which involve regulated exocytosis. Expression of the encoded protein in human pancreatic islets has been connected to activity of the promoter for the insulin gene, on the same chromosome several hundred kilobases away (PMID: 21336277 and 22928559). This association would link response to gluclose to insulin secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: SYT8\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Synaptotagmin-8\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8NBV8; Mouse: Q9R0N6; Rat: Q925B4\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Synaptotagmin-8;Synaptotagmin VIII;SytVIII\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 90019\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239377789107,"sku":"BT-AP14661-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239377821875,"sku":"BT-AP14661-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239377854643,"sku":"BT-AP14661-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_41c9f1bf-81e6-460b-a49c-ca0d84b436b1.png?v=1769393665","url":"https:\/\/afsbio.com\/products\/syt8-polyclonal-antibody-bt-ap14661","provider":"AFSBio Inc.","version":"1.0","type":"link"}