{"product_id":"t-type-ca-cp-α1h-p492-polyclonal-antibody-bs3413","title":"T-type Ca++ CP α1H (P492) Polyclonal Antibody-BS3413","description":"\u003cp\u003eT-type Ca++ CP α1H (P492) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3413-50, BS3413-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Voltage-dependent T-type calcium channel subunit alpha-1H; Low-voltage-activated calcium channel alpha1 3.2 subunit; Voltage-gated calcium channel subunit alpha Cav3.2; CACNA1H\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O95180\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Voltage-dependent Ca++ channels mediate Ca++ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca++-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an α1 subunit, an intracellular β subunit, a disulfide linked α2\/δ subunit and a transmembrane γ subunit. Ca++ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. T-type Ca++ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca++ current types. T-type Ca++ channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs).\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: T-type Ca++ CP α1H (P492) polyclonal antibody detects endogenous levels of T-type Ca++ CP α1H protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 315 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of T-type Ca++ CP α1H (P492) pAb at 1:500 dilution\u003cbr\u003e\nLane 1: L02 whole cell lysate(40ug)\u003cbr\u003e\nLane 2: HepG2 whole cell lysate(40ug)\u003cbr\u003e\nLane 3: PC3 whole cell lysate(20ug)\u003cbr\u003e\nLane 4: AML-12 whole cell lysate(40ug)\u003cbr\u003e\nLane 5: H9C2 whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 461-510 of Human T-type Ca++ CP α1H.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42911805079731,"sku":"BS3413-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42911805112499,"sku":"BS3413-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_3b7df535-893f-4ea5-b86c-7dae8e366a6a.jpg?v=1703179591","url":"https:\/\/afsbio.com\/products\/t-type-ca-cp-%ce%b11h-p492-polyclonal-antibody-bs3413","provider":"AFSBio Inc.","version":"1.0","type":"link"}