{"product_id":"tab2-monoclonal-antibody-bt-mca3729","title":"TAB2 Monoclonal Antibody - BT-MCA3729","description":"\u003cp\u003eTAB2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3729-50, BT-MCA3729-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is an activator of MAP3K7\/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8\/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11\/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A\/RANK), which may regulate the development and function of osteoclasts.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction, Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TAB2\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3B5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TAB2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human TAB2 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 80kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q9NYJ8\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: CHTD2, FLJ21885, KIAA0733, MAP3K7IP2, TAB2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 23118\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238612787379,"sku":"BT-MCA3729-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238612820147,"sku":"BT-MCA3729-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d6469d26-2820-4b2f-9dfc-1b96a5630f65.png?v=1769383069","url":"https:\/\/afsbio.com\/products\/tab2-monoclonal-antibody-bt-mca3729","provider":"AFSBio Inc.","version":"1.0","type":"link"}