{"product_id":"tab3-polyclonal-antibody-ra35198","title":"TAB3 Polyclonal Antibody - RA35198","description":"\u003cp\u003eTAB3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA35198-50, RA35198-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: TGF-beta activated kinase 1\/MAP3K7 binding protein 3 (TAB3) Homo sapiens The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2\/TAB2, forms a ternary complex with the protein kinase MAP3K7\/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7\/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 257397\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 78\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q8N5C8\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120628261043,"sku":"RA35198-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120628293811,"sku":"RA35198-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ddcdc1f7-6f18-49aa-81e3-1dff1b751639.png?v=1773368744","url":"https:\/\/afsbio.com\/products\/tab3-polyclonal-antibody-ra35198","provider":"AFSBio Inc.","version":"1.0","type":"link"}