{"product_id":"tau-acetyl-lys174-polyclonal-antibody-bt-ap14754","title":"Tau (Acetyl Lys174) Polyclonal Antibody - BT-AP14754","description":"\u003cp\u003eTau (Acetyl Lys174) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14754-20, BT-AP14754-50, BT-AP14754-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimerandapos;s disease, Pickandapos;s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Neuroscience; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MAPT\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Microtubule-associated protein tau\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P10636; Mouse: P10637; Rat: P19332\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Microtubule-associated protein tau;Neurofibrillary tangle protein;Paired helical filament-tau;PHF-tau; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 4137\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239381524659,"sku":"BT-AP14754-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239381557427,"sku":"BT-AP14754-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239381590195,"sku":"BT-AP14754-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3810062f-d65b-4cd1-8ad8-bc83251fce24.png?v=1769393735","url":"https:\/\/afsbio.com\/products\/tau-acetyl-lys174-polyclonal-antibody-bt-ap14754","provider":"AFSBio Inc.","version":"1.0","type":"link"}