{"product_id":"tau-monoclonal-antibody-e-ab-22141","title":"Tau Monoclonal Antibody - E-AB-22141","description":"\u003cp\u003eTau Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-22141-60, E-AB-22141-120, E-AB-22141-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Tau Mouse (10E3)\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: AI413597; AW045860; DDPAC; FLJ31424; FTDP 17; G protein beta1\/gamma2 subunit interacting factor 1; MAPT; MAPTL; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau; Microtubule associated protein tau isoform 4; Microtubule-associated protein tau; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Paired helical filament tau; Paired helical filament-tau; PHF tau; PHF-tau; PPND; PPP1R103; Protein phosphatase 1; regulatory subunit 103; pTau; RNPTAU; TAU; TAU; Tauopathy and respiratory failure; included\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Neuroscience, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC-p\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone No.: Clone:8A3\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P10636\u003c\/p\u003e\n\n\u003cp\u003eBackground: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic Peptide of Tau\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Protein A purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1000-2000, IHC 1:100-200\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 79kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43148620071091,"sku":"E-AB-22141-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43148620103859,"sku":"E-AB-22141-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43148620136627,"sku":"E-AB-22141-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_40b746cf-79ec-4092-a1d7-313ee629c51b.png?v=1710326858","url":"https:\/\/afsbio.com\/products\/tau-monoclonal-antibody-e-ab-22141","provider":"AFSBio Inc.","version":"1.0","type":"link"}