{"product_id":"tau-phospho-s519-polyclonal-antibody-bs4914","title":"Tau  (phospho-S519) Polyclonal Antibody - BS4914","description":"\u003cp\u003eTau  (phospho-S519) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS4914-50, BS4914-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tau, also known as MAPT (microtubμle-associated protein tau), MAPTL, MTBT1 or TAU, is a 758 amino acid protein that localizes to the cytoplasm, as well as to the cytoskeleton and the cell membrane, and contains four Tau\/MAP repeats. Expressed in neuronal tissue and existing as mμltiple alternatively spliced isoforms, Tau functions to promote microtubμle assembly and stability and is thought to be involved in the maintenance of neuronal polarity. Tau may also link microtubμles with neural plasma membrane components and, addition to its role in microtubμle stability, is also necessary for cytoskeletal plasticity.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Microtubμle-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Phosphorylated\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic phosphopeptide derived from human Tau around the phosphorylation site of Serine 519\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Tau (phospho-S519) polyclonal antibody detects endogenous levels of Tau protein only when phosphorylated at Ser519.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 50-80 kDa\u003c\/p\u003e\n\n\u003cp\u003ePathway: Neuronal and Glial Cell Marker Atlas, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,\u003c\/p\u003e \n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P10636\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45946322223283,"sku":"BS4914-50","price":289.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45946322256051,"sku":"BS4914-100","price":492.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/tau-phospho-s519-polyclonal-antibody-bs4914","provider":"AFSBio Inc.","version":"1.0","type":"link"}