{"product_id":"tbcb-polyclonal-antibody-e-ab-64516","title":"TBCB Polyclonal Antibody - E-AB-64516","description":"\u003cp\u003eTBCB Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-64516-60, E-AB-64516-120, E-AB-64516-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TBCB\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: TBCB; CG22; CKAP1; CKAPI\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q99426\u003c\/p\u003e\n\n\u003cp\u003eBackground: Microtubules, the primary component of the cytoskeletal network, are highly dynamic structures composed of α\/β Tubulin heterodimers. Biosynthesis of functional microtubules involve the participation of several chaperones, termed Tubulin folding cofactors A (TBCA), B (TBCB), D (TBCD), E (TBCE) and C (TBCC), that act on folding intermediates downstream of the cytosolic chaperon, alternatively named TCP. TBCB (tubulin folding cofactor B), also known as CG22, CKAP1 or CKAPI, is a 244 amino acid cytoplasmic protein containing one CAP-Gly domain and in widely expressed. TBCB is involved in the regulation of tubulin heterodimer dissociation and may function as a negative regulator of axonal growth.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human TBCB (NP_001272.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136897188019,"sku":"E-AB-64516-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136897220787,"sku":"E-AB-64516-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136897253555,"sku":"E-AB-64516-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_49e4a03f-dd1e-405d-a562-462907339fa8.png?v=1709993619","url":"https:\/\/afsbio.com\/products\/tbcb-polyclonal-antibody-e-ab-64516","provider":"AFSBio Inc.","version":"1.0","type":"link"}