{"product_id":"tbl1xr1-monoclonal-antibody-ra12061","title":"TBL1XR1 Monoclonal Antibody - RA12061","description":"\u003cp\u003eTBL1XR1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA12061-50, RA12061-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: transducin beta like 1 X-linked receptor 1 (TBL1XR1) Homo sapiens This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta) -like 1X-linked (TBL1X) . The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC-p; IF\/ICC\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat; Bovine; Chicken; Dog; Pig; Zebrafish\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 79718\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9BZK7\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45118999756979,"sku":"RA12061-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45118999789747,"sku":"RA12061-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_edb22c72-3dec-49bc-b1ba-6c7b14e4e082.png?v=1773344085","url":"https:\/\/afsbio.com\/products\/tbl1xr1-monoclonal-antibody-ra12061","provider":"AFSBio Inc.","version":"1.0","type":"link"}