{"product_id":"tbp-tata-binding-protein-monoclonal-antibody-1f6-ra10647","title":"TBP\/TATA Binding Protein Monoclonal Antibody (1F6) - RA10647","description":"\u003cp\u003eTBP\/TATA Binding Protein Monoclonal Antibody (1F6)\u003c\/p\u003e \n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA10647-50, RA10647-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: TATA-box binding protein (TBP) Homo sapiens Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA bin\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p; IF (paraffin section)\u003c\/p\u003e \n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 6908\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 35-45\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P20226\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45119017910451,"sku":"RA10647-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45119017943219,"sku":"RA10647-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e95233cb-7c47-4d19-9dae-427da83602f4.png?v=1773344318","url":"https:\/\/afsbio.com\/products\/tbp-tata-binding-protein-monoclonal-antibody-1f6-ra10647","provider":"AFSBio Inc.","version":"1.0","type":"link"}