{"product_id":"tbx21-polyclonal-antibody-bt-ap14805","title":"TBX21 Polyclonal Antibody - BT-AP14805","description":"\u003cp\u003eTBX21 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14805-20, BT-AP14805-50, BT-AP14805-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21\/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Stem cells; Immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TBX21\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: T-box transcription factor TBX21\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9UL17; Mouse: Q9JKD8\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: T-box transcription factor TBX21;T-box protein 21;T-cell-specific T-box transcription factor T-bet;Transcription factor TBLYM\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 30009\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239383130291,"sku":"BT-AP14805-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239383163059,"sku":"BT-AP14805-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239383195827,"sku":"BT-AP14805-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_09a17bee-4c0d-4aa9-9bc4-a8a28d5eed6b.png?v=1769393757","url":"https:\/\/afsbio.com\/products\/tbx21-polyclonal-antibody-bt-ap14805","provider":"AFSBio Inc.","version":"1.0","type":"link"}