{"product_id":"tbx21-polyclonal-antibody-e-ab-67622","title":"TBX21 Polyclonal Antibody - E-AB-67622","description":"\u003cp\u003eTBX21 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-67622-60, E-AB-67622-120, E-AB-67622-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TBX21\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: TBX21; T-PET; T-bet; TBET; TBLYM; T-box 21\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9UL17\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21\/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human TBX21 (NP_037483.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:1000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 58kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 58kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43148686819507,"sku":"E-AB-67622-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43148686852275,"sku":"E-AB-67622-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43148686885043,"sku":"E-AB-67622-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2ed211b7-beb1-4b6d-96cd-7958f68bf9ce.png?v=1710328059","url":"https:\/\/afsbio.com\/products\/tbx21-polyclonal-antibody-e-ab-67622","provider":"AFSBio Inc.","version":"1.0","type":"link"}