{"product_id":"tbx5-monoclonal-antibody-bt-mca3066","title":"TBX5 Monoclonal Antibody - BT-MCA3066","description":"\u003cp\u003eTBX5 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3066-50, BT-MCA3066-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: TBX5, also known as T-box 5. It is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The TBX5 protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling, Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TBX5\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 7B11\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TBX5\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of TBX5 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 53kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q99593\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HOS, TBX5\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 6910\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238639493299,"sku":"BT-MCA3066-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238639526067,"sku":"BT-MCA3066-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8c7225e5-2332-4ddc-8f79-eccabfe9c9f9.png?v=1769383315","url":"https:\/\/afsbio.com\/products\/tbx5-monoclonal-antibody-bt-mca3066","provider":"AFSBio Inc.","version":"1.0","type":"link"}