{"product_id":"tcf-4-12-polyclonal-antibody-ra21276","title":"TCF-4\/12 Polyclonal Antibody - RA21276","description":"TCF-4\/12 Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA21276-50, RA21276-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: transcription factor 4 (TCF4) Homo sapiens This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to \u0026gt;50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Jul 2016],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/20000. Not yet tested in other applications.\n\nAlternative Names: TCF4; BHLHB19; ITF2; SEF2; Transcription factor 4; TCF-4; Class B basic helix-loop-helix protein 19; bHLHb19; Immunoglobulin transcription factor 2; ITF-2; SL3-3 enhancer factor 2; SEF-2; TCF12; BHLHB20; HEB; HTF4; Transcription factor 12;\n\nApplications: WB; IHC-p; IF (paraffin section) ; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 6925\/6938\n\nProtein MW (KDa): 60\n\nSWISS: P15884\/Q99081\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121056604339,"sku":"RA21276-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121056637107,"sku":"RA21276-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_75c87265-3b22-468b-9293-5ff0551d7812.png?v=1773370141","url":"https:\/\/afsbio.com\/products\/tcf-4-12-polyclonal-antibody-ra21276","provider":"AFSBio Inc.","version":"1.0","type":"link"}