{"product_id":"tdp-43-tardb-polyclonal-antibody-bs6221","title":"TDP-43\/TARDB Polyclonal Antibody-BS6221","description":"\u003cp\u003eTDP-43\/TARDB Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50 µl, 100 µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS6221-50, BS6221-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q13148\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eTDP-43\/TARDB Polyclonal Antibody-BS6221\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IP, , RIP,\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB,1:500 - 1:2000  |  IP,1:50 - 1:100  |  RIP,1:20 - 1:50\u003c\/p\u003e\n\n\u003cp\u003eBackground: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 42kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of extracts of various cell lines, using TDP-43\/TARDB antibody at 1:1000 dilution.\u003cbr\u003e\nSecondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.\u003cbr\u003e\nLysates\/proteins: 25ug per lane.\u003cbr\u003e\nBlocking buffer: 3% non-fat dry milk in TBST., Immunoprecipitation analysis of 200ug extracts of SW620 cells using 3ug TDP-43\/TARDB antibody. Western blot was performed from the immunoprecipitate using TDP-43\/TARDB antibody at a dilution of 1:500.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ALS10; TDP-43; TARDBP; TDP43\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human TDP-43\/TARDB(NP_031401.1).\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42962851594419,"sku":"BS6221-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42962851627187,"sku":"BS6221-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_6feea1ef-c945-4bcc-a620-8c283b236b56.jpg?v=1705319340","url":"https:\/\/afsbio.com\/products\/tdp-43-tardb-polyclonal-antibody-bs6221","provider":"AFSBio Inc.","version":"1.0","type":"link"}