{"product_id":"tdp43-monoclonal-antibody-bt-mca4192","title":"TDP43 Monoclonal Antibody - BT-MCA4192","description":"\u003cp\u003eTDP43 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4192-50, BT-MCA4192-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TDP43\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 6G2D8\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: TDP43\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human TDP43 (AA: free peptide) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 44.7kDa\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ALS10, TDP-43\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 23435\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238361686195,"sku":"BT-MCA4192-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238361718963,"sku":"BT-MCA4192-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c90aa02d-5385-41f5-9d91-9aa77172cc6b.png?v=1769379183","url":"https:\/\/afsbio.com\/products\/tdp43-monoclonal-antibody-bt-mca4192","provider":"AFSBio Inc.","version":"1.0","type":"link"}